Online Extension Courses

Does anyone have any opinions about taking classes online from a four-year university Extension Program?
I would believe that the general pre-reqs will not be accepted, but would a Genetics course?

That is a question you have to ask the schools you plan to attend. It does seem (in general) that DO schools do not differentiate between Community Colleges/Universities/Online classes for any of their pre reqs. I have heard there are a number of MD schools that DO NOT accept anything but university attended classes.
In anycase, i took/am taking all my pre reqs online (already have a degree) from a CC and the schools i have talked to did not care.
Good luck!